High throughput protein crystallography: Developments in crystallisation, data collection and data processing

Until recently, individual protein structure determination using protein X-ray crystallography was often a protracted and resource intensive process, sometimes taking years. To address this, the past decade has seen the emergence of high throughput protein crystallography. Here we seek to review broadly the technological advances in protein crystallisation, X-ray data collection and X-ray data processing that have helped to make high throughput crystallography possible.

Section editor:Hugo Kubinyi – University of Heidelberg, Heidelberg, Germany