Retinal neuroprotection in dry age-related macular degeneration

Dry age-related macular degeneration (AMD) is a slowly progressive visual disorder that is a leading cause for severe visual impairment in the elderly population. Clinical options to prevent disease development and progression are very limited at this time. Recently, research on dry AMD has begun to focus on retinal neuroprotection strategies to prevent apoptosis and necrosis, reduce oxidative injury and understand the molecular and cellular response to neuroprotective agents. Here we review the most recent advances in basic and clinical research in neuroprotection as it relates to dry AMD.