کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2082903 | 1545272 | 2010 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Aging control with resveratrol
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
بیوتکنولوژی یا زیستفناوری
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چکیده انگلیسی
The prevalence of age-related pathologies such as neurodegenerative disease and diabetes type II has increased with rise in average age of people. Finding antiaging molecules is necessary to prevent or delay the alterations taking place in age which are manifested as age-associated illnesses. Currently, dietary restriction (DR) is one of the most effective antiaging interventions. Thus, the biochemical pathways involved in DR lifespan increase are under intensive investigation. Sirtuin 1 and mTOR (mammalian target of rapamycin) are two well characterized antiaging pathways. Resveratrol constitutes a natural compound which mimics the effects of DR with potential application on age-associated diseases and thus as antiaging therapy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Drug Discovery Today: Therapeutic Strategies - Volume 7, Issues 3–4, Winter 2010, Pages 51–56
Journal: Drug Discovery Today: Therapeutic Strategies - Volume 7, Issues 3–4, Winter 2010, Pages 51–56
نویسندگان
Mercè Pallàs, Felix Junyent, Ester Verdaguer, Carlos Beas-Zarate, Antoni Camins,