Unraveling the complexities of neurogenesis to guide development of CNS therapeutics

The discovery of neurogenesis in the adult mammalian central nervous system (CNS) has led to a dramatic shift in our understanding of brain plasticity and the role it plays in mood disorders. As research in the field continues and the ability to intervene pharmacologically at key stages in the process of neurogenesis becomes a reality, so too does the goal of using neurogenesis to develop improved treatments for disorders of the CNS.

Section editors:David Sibley – National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, USAC. Anthony Altar – Psychiatric Genomics, Gaithersburg, USATheresa Branchek – Lundbeck Research, Paramus, USA