کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2084429 | 1545382 | 2010 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Small-animal PET: A promising, non-invasive tool in pre-clinical research Small-animal PET: A promising, non-invasive tool in pre-clinical research](/preview/png/2084429.png)
Today, non-invasive imaging techniques are significantly contributing to the understanding of molecular processes in vivo. Positron emission tomography (PET) is a scintigraphic medical imaging modality that uses radiolabelled molecules (tracers), provides quantitative tomographic images and allows non-invasive assessment of the biodistribution of radioactive substances in vivo. The assessment of pathological glucose metabolism is the clinically best-established application of PET today; however, a multitude of different tracers are available to assess diverse physiological processes. The growing interest in pre-clinical imaging studies, in biological and medical basic research, as well as in pharmaceutical research, has fostered the recent growth in small-animal PET. Small-animal PET can be applied to enable the transfer from molecular findings in vitro to in vivo applications in humans, from bench to bed side.
Journal: European Journal of Pharmaceutics and Biopharmaceutics - Volume 74, Issue 1, January 2010, Pages 50–54