کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2086072 1545508 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Profil Imunohistokimia Superoksida Dismutase (SOD) pada Jaringan Hati Tikus dengan Kondisi Hiperkolesterolemia
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک بوم شناسی، تکامل، رفتار و سامانه شناسی
پیش نمایش صفحه اول مقاله
Profil Imunohistokimia Superoksida Dismutase (SOD) pada Jaringan Hati Tikus dengan Kondisi Hiperkolesterolemia
چکیده انگلیسی

This study was conducted to observe intracellular antioxidant cooper,zinc-superoxide dismutase (Cu,Zn-SOD) in liver tissue of rats under hypercholesterolemic condition by using immunohistochemical technique. A total of twenty male Wistar rats were used for this study. Those rats were divided into two groups; (i) control group and (ii) hypercholesterolemic group, which were fed died containing 1% cholesterol for eight weeks. Rat livers were taken at the end of treatment, and processed by using paraffin embedding standard method. The tissues were stained immunohistochemically to Cu,Zn-SOD. Observation of Cu,Zn-SOD content in the tissue was performed qualitatively in the cytoplasm and quantitatively in the nucleus of hepatocytes based on colour intensity of enzyme reaction product. The profile of antioxidant-Cu,Zn-SOD decreased (P < 0.05) in the hypercholesterolemic group compared to the control group.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: HAYATI Journal of Biosciences - Volume 13, Issue 3, September 2006, Pages 85–89
نویسندگان
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