کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2087637 1080677 2013 15 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Assessing colorectal cancer heterogeneity: one step closer to tailored medicine
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوتکنولوژی یا زیست‌فناوری
پیش نمایش صفحه اول مقاله
Assessing colorectal cancer heterogeneity: one step closer to tailored medicine
چکیده انگلیسی

SummaryMany advances in understanding colorectal cancer heterogeneity and its impact on the variability of treatment efficacy have been achieved in recent years. New methods have also been introduced in colorectal cancer diagnosis and early detection, including molecular biology techniques as well as newly developed or improved imaging techniques. We are currently aware of some aspects of colorectal cancer heterogeneity, such as alterations in the epidermal growth factor receptor signalling or the different behaviours of tumours belonging to different genetic and epigenetic subtypes. In the future, greater attention should also be focused on other signalling circuits with the goal to treat patients individually, based on the characteristics of their tumours. This so-called personalised medicine will bring more benefits to patients, without unnecessary adverse side effects. Therefore, all new information regarding colorectal cancer biology brings us one step closer to accomplishing this goal.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Applied Biomedicine - Volume 11, Issue 3, 2013, Pages 115–129
نویسندگان
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