کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2097241 | 1082206 | 2007 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Effects of caffeine on in vivo and in vitro oocyte maturation in mice
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Effects of caffeine on in vivo and in vitro oocyte maturation in mice Effects of caffeine on in vivo and in vitro oocyte maturation in mice](/preview/png/2097241.png)
چکیده انگلیسی
The objective was to investigate, using a mouse model, the effects of caffeine on the number of ovulated oocytes, the rate of oocyte maturation, the susceptibility of oocytes to activating stimuli, spindle morphology, and distribution of cortical granules (CGs). Mice were given caffeine (150 mg/kg body weight ip) at various times relative to hCG (−2, 0, and +2 h); in an in vitro study, 1, 5 or 10 mM caffeine was added to the maturation culture. Caffeine had no effect on the quality of oocytes in vivo maturation, but caffeine was detrimental to the quality of oocytes matured in vitro. Further studies are needed to determine caffeine concentration in follicles relative to that in culture medium.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Theriogenology - Volume 68, Issue 4, 1 September 2007, Pages 640–645
Journal: Theriogenology - Volume 68, Issue 4, 1 September 2007, Pages 640–645
نویسندگان
Yi-Liang Miao, Li-Hong Shi, Zi-Li Lei, Jun-Cheng Huang, Ji-Wen Yang, Ying-Chun OuYang, Qing-Yuan Sun, Da-Yuan Chen,