کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2114534 | 1084543 | 2009 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Cancer stem cell marker expression in hepatocellular carcinoma and liver metastases is not sufficient as single prognostic parameter
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
تحقیقات سرطان
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Cancer stem cell marker expression in hepatocellular carcinoma and liver metastases is not sufficient as single prognostic parameter Cancer stem cell marker expression in hepatocellular carcinoma and liver metastases is not sufficient as single prognostic parameter](/preview/png/2114534.png)
چکیده انگلیسی
Recent findings suggest that the presence of cancer stem cells could be linked with patients’ survival. We profiled suggested cancer stem cell markers in tissue specimens of hepatocellular carcinoma and colorectal carcinoma liver metastases. About 1% of cells co-expressed cancer stem cell antigens, but there was no correlation between the amount of CD133+, CD133+/CD44+ or CD133+/CD24− cells and the patients’ clinical–pathological status or with the cancer stem cell marker-positive cells localization. CD133+ and CD133− fractions of Huh7 cells did not differ in migratory properties. Therefore, presence of markers alone should be taken with caution as single prognostic parameters.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Cancer Letters - Volume 275, Issue 2, 18 March 2009, Pages 185–193
Journal: Cancer Letters - Volume 275, Issue 2, 18 March 2009, Pages 185–193
نویسندگان
Alexei V. Salnikov, Grace Kusumawidjaja, Vanessa Rausch, Helge Bruns, Wolfgang Gross, Akmal Khamidjanov, Eduard Ryschich, Martha-Maria Gebhard, Gerhard Moldenhauer, Markus W. Büchler, Peter Schemmer, Ingrid Herr,