کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2114798 1084556 2008 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Enhancement of adipogenesis induction by conditioned media obtained from cancer cells
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
Enhancement of adipogenesis induction by conditioned media obtained from cancer cells
چکیده انگلیسی

White adipose tissue is a multifunctional endocrine organ that synthesizes and secretes cytokine-like proteins termed adipokines. In the present study, the effects of cancer-derived medium on adipogenesis were examined. We prepared conditioned media from cancer cell lines, and cultured preadipocytes in the conditioned media. After 10 days of culture, intracellular lipid droplet accumulation was measured. We observed that the conditioned media significantly induced adipogenesis or enhanced the adipogenesis induced by adipogenesis inducers. Although we could not define the factors, these undefined factors derived from cancer cells may induce adipogenesis, and the resulting adipogenesis may affect cancer development.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Cancer Letters - Volume 268, Issue 2, 18 September 2008, Pages 286–294
نویسندگان
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