کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2115123 1084576 2007 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Progesterone receptor expression is a marker for early stage breast cancer: Implications for progesterone receptor as a therapeutic tool and target
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
Progesterone receptor expression is a marker for early stage breast cancer: Implications for progesterone receptor as a therapeutic tool and target
چکیده انگلیسی

We determined the association of estrogen receptor (ER) and progesterone receptor (PR) expression in invasive breast cancer with stage at diagnosis. Univariate analyses indicated that although ER and PR expression were inversely associated with grade (P < 0.0001), only PR expression (P < 0.01) was inversely associated with stage. Multivariate analyses, adjusted for covariates, including HER-2/neu expression, indicated that PR (odds ratio (OR), 0.88; confidence interval (CI), 0.77–0.99; P = 0.03) and not ER expression (OR, 1.04; CI, 0.94–1.16; P = 0.45) was inversely associated with stage. PR and not ER expression is a marker for early stage breast cancer.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Cancer Letters - Volume 258, Issue 2, 18 December 2007, Pages 253–261
نویسندگان
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