کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2115743 | 1084608 | 2006 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The association between microsomal epoxide hydrolase genotypes and esophageal squamous-cell-carcinoma in Taiwan: Interaction between areca chewing and smoking
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
تحقیقات سرطان
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: The association between microsomal epoxide hydrolase genotypes and esophageal squamous-cell-carcinoma in Taiwan: Interaction between areca chewing and smoking The association between microsomal epoxide hydrolase genotypes and esophageal squamous-cell-carcinoma in Taiwan: Interaction between areca chewing and smoking](/preview/png/2115743.png)
چکیده انگلیسی
One hundred and forty-five ESCC patients and 352 controls were recruited from three hospitals in Taiwan to determine the association between esophageal squamous-cell-carcinoma (ESCC) and microsomal epoxide hydrolase (mEH) genotypes at Thy113His and His139Arg. Stratified by their exposures, the His113His genotype was a significant protective factor for ESCC in areca chewers and tobacco smokers. Stratified by His113 polymorphisms, the risk of contracting ESCC for participants with His113His who chewed areca and smoked was >50% less than for those with Thy113Thy. We suggest that the mEH His113His genotype can differentiate the association between smoking, areca chewing, and ESCC.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Cancer Letters - Volume 237, Issue 2, 18 June 2006, Pages 281–288
Journal: Cancer Letters - Volume 237, Issue 2, 18 June 2006, Pages 281–288
نویسندگان
Ying-Chu Lin, Deng-Chyang Wu, Jang-Ming Lee, Hon-Ki Hsu, Ein-Long Kao, Chien-Hui Yang, Ming-Tsang Wu,