کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2124534 1547269 2007 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Important prognostic factors for the long-term survival of subjects with primary liver cancer in Taiwan: A hyperendemic area
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
Important prognostic factors for the long-term survival of subjects with primary liver cancer in Taiwan: A hyperendemic area
چکیده انگلیسی

This study used a large-scale cancer database in determining the survival prognostic factors among primary liver cancer (PLC) subjects. A total of 28,939 subjects diagnosed with PLC were analysed. Survival estimates were performed with Kaplan–Meier methods. Cox’s proportional-hazards model estimated the death risk (hazard ratio (HR)) of prognostic factors. The prognostic indicators associated with higher risk of all-cause deaths are male gender (males versus females; HR = 1.16, 95% confidence intervals (CI), 1.13–1.20), diagnosis at later period (shown in 1990–1994 versus 1985–1989; HR = 1.04, 95% CI, 1.01–1.08), increasing age at diagnosis, subjects with adenocarcinoma/cholangiocarcinoma (CC) and with no therapy against those with chemotherapy. The overall 5-year survival rate for all causes of death was significantly poorer in males (13.7%) than females (17.2%). Subjects diagnosed with hepatoblastoma and treated by surgical resection alone had superior prognosis. Particularly, subjects with adenocarcinoma and CC were more likely to die in other metastatic cancer.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Cancer - Volume 43, Issue 6, April 2007, Pages 1076–1084
نویسندگان
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