کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2124534 | 1547269 | 2007 | 9 صفحه PDF | دانلود رایگان |

This study used a large-scale cancer database in determining the survival prognostic factors among primary liver cancer (PLC) subjects. A total of 28,939 subjects diagnosed with PLC were analysed. Survival estimates were performed with Kaplan–Meier methods. Cox’s proportional-hazards model estimated the death risk (hazard ratio (HR)) of prognostic factors. The prognostic indicators associated with higher risk of all-cause deaths are male gender (males versus females; HR = 1.16, 95% confidence intervals (CI), 1.13–1.20), diagnosis at later period (shown in 1990–1994 versus 1985–1989; HR = 1.04, 95% CI, 1.01–1.08), increasing age at diagnosis, subjects with adenocarcinoma/cholangiocarcinoma (CC) and with no therapy against those with chemotherapy. The overall 5-year survival rate for all causes of death was significantly poorer in males (13.7%) than females (17.2%). Subjects diagnosed with hepatoblastoma and treated by surgical resection alone had superior prognosis. Particularly, subjects with adenocarcinoma and CC were more likely to die in other metastatic cancer.
Journal: European Journal of Cancer - Volume 43, Issue 6, April 2007, Pages 1076–1084