کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2124913 | 1547279 | 2006 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Chewing gum and risk of oesophageal adenocarcinoma: A new hypothesis tested in a population-based study
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
تحقیقات سرطان
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The aim of this study was to test the hypothesis that chewing gum is associated with risk of oesophageal and cardia adenocarcinoma. A Swedish nationwide, population-based, case-control study was conducted in 1995-1997. All patients were prospectively and uniformly documented and classified shortly after diagnosis. In all, 189 and 262 patients with oesophageal and cardia adenocarcinoma, respectively, and 820 population-based control subjects were interviewed. These patients together constituted 85% of eligible cases occurring in Sweden. Odds ratios (OR) with 95% confidence intervals (CI) were calculated by multivariable logistic regression with adjustment for plausible confounders. Regular users of chewing gum (P3 times/week for P6 months) were not at increased risk of oesophageal adenocarcinoma (OR 1.0, 95% CI 0.6-2.2), and no duration-response relation was observed (PÂ =Â 0.38). No association between regular gum chewing and cardia adenocarcinoma was found (OR 1.0, 95% CI 0.6-1.7), irrespective of duration of use (PÂ =Â 0.56). In conclusion, with regard to risk of oesophageal or cardia adenocarcinoma, gum chewing seems harmless.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Cancer - Volume 42, Issue 14, September 2006, Pages 2359-2362
Journal: European Journal of Cancer - Volume 42, Issue 14, September 2006, Pages 2359-2362
نویسندگان
Jesper Lagergren, Catarina Jansson, Pernilla Viklund,