The mutation of DBC2 in breast cancer patients from the Han ethnic group in Eastern China

Mutation in the promoter and exon 7 of DBC2 gene is not common in the Chinese population and may not contribute to the susceptibility for breast cancer in China. The intronic alteration IVS7 + 53C > G is a common polymorphism in the Chinese Han ethnic group. Further research is warranted to evaluate the relationship between IVS7 + 53C > G and the susceptibility for breast cancer.