کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2143915 1088364 2007 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Patient attitudes towards chemotherapy as assessed by patient versus physician: A prospective observational study in advanced non-small cell lung cancer
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
Patient attitudes towards chemotherapy as assessed by patient versus physician: A prospective observational study in advanced non-small cell lung cancer
چکیده انگلیسی

SummaryBackgroundIn the treatment of advanced cancer, a physician's ability to accurately identify a patient's attitude towards treatment is critical. This paper describes the extent of any differences observed between patient attitudes towards chemotherapy for advanced non-small cell lung cancer (NSCLC) as assessed by patients themselves versus their physicians.Patients and methodsPatients with stage IIIB or IV NSCLC who received gemcitabine plus cisplatin or carboplatin were enrolled into this prospective observational study. Patients and their physicians completed questionnaires containing descriptions of seven patient-specific attitudes. A pre-defined algorithm was used to categorize patients into one of the three ‘need’ categories based on the questionnaire responses: (A) “maximum extension of survival with acceptance of high toxicity”, (B) “maximum extension of survival only if coupled with normal life style”, and (C) “relief of symptoms”. Each patient was categorized based on his own response, as well as his physician's response.ResultsA total of 1895 patients were enrolled from 19 countries across 3 continents. Data from 1884 patients were analysed. Based on patient versus physician responses, respectively, the distribution of patients was 60% versus 39% in need category A, 26% versus 33% in B, and 14% versus 29% in C. Patient self-assessed versus physician-assessed need category identification was aligned for 891 patients (47.3%): 541 (29%) in A, 218 (12%) in B, 132 (7%) in C. While there was slight agreement between the identification of ‘need’ categories by physicians and patients (kappa = 0.18, 95% CI: 0.15–0.21), physicians also tended to place patients further down the scale (towards C) than patients placed themselves (P < 0.001).ConclusionsPatients have varying needs from cancer chemotherapy and it may not always be correctly identified by the treating physician. Physicians may underestimate patient's desire for extended survival compared with symptom relief.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Lung Cancer - Volume 56, Issue 3, June 2007, Pages 433–443
نویسندگان
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