کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2159278 1090854 2009 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Intra-operative pubic arch interference during prostate seed brachytherapy in patients with CT-based pubic arch interference of ⩽1 cm
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
Intra-operative pubic arch interference during prostate seed brachytherapy in patients with CT-based pubic arch interference of ⩽1 cm
چکیده انگلیسی

PurposeThere are only a few reports on the frequency of intra-operative pubic arch interference (I-PAI) during prostate seed brachytherapy (PB).Materials and methodsTwo hundred and forty-three patients with a CT-based pubic arch interference (PAI) of ⩽1 cm and a prostate volume of ⩽50–60 cc underwent PB. Those patients requiring needle repositioning by ⩾0.5 cm on the template were scored as having I-PAI. The incidence of I-PAI and its impact on biochemical control were analyzed.ResultsIntra-operative PAI was encountered in 47 (19.3%) patients. Forty two patients (17.3%) had I-PAI in 1–2 needles, two (0.8%) had I-PAI in four needles and three patients (1.2%) had I-PAI in six needles. Overall, 1.4% of needles required repositioning due to I-PAI. BMI > 27 kg/m2 and wider (>75 mm) pubic bone separation at mid ramus (PS-ML) were associated with a lower incidence of I-PAI. At a median follow-up of 50.1 months, the 3- and 5-year bPFS was 97.3% and 95.2%, respectively. The 5-year bPFS rates for patients with and without I-PAI were 95.6% and 95%, respectively (p = 0.28).ConclusionsThe use of CT-based PAI of ⩽1 cm as a selection criterion for PB is a simple and reliable method for minimizing the incidence of I-PAI and maintaining excellent biochemical control rates.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Radiotherapy and Oncology - Volume 91, Issue 2, May 2009, Pages 249–254
نویسندگان
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