کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2160279 1090878 2008 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Detection of intrafractional tumour position error in radiotherapy utilizing cone beam computed tomography
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
Detection of intrafractional tumour position error in radiotherapy utilizing cone beam computed tomography
چکیده انگلیسی

PurposeTo study the intrafraction tumour position error utilizing cone beam CT (CBCT) in patients receiving radiotherapy.Methods and materialsFifty-four patients were treated with Elekta Synergy S system, including 19 head and neck, 25 thoracic and 10 abdominal-pelvic tumours. All patients received CBCT after initial setup and some of them received CBCT after correction and after treatment. CBCT were registered to planning CT and errors of isocenter position on the left-to-right (LR), superior–inferior (SI) and anterior–posterior (AP) directions were analyzed.ResultsAfter treatment the systematic (Σ) and random uncertainty (σ) increased, the increments of tumour Σ were 0.1–0.3, 0.2–0.5 and 0.2–0.6 mm, respectively, while the increments of σ were 0.1–0.3, 0.2–0.4 and 0.1–0.4 mm, respectively, for the head and neck, thoracic and abdominal-pelvic tumours. Based on 380 paired pre- and post-treatment CBCT, the intrafraction errors (mean ± SD) in the LR, SI and AP directions were −0.1 ± 0.9, −0.3 ± 1.0 and −0.2 ± 0.7 mm, respectively, for head and neck tumours, −0.1 ± 1.2, −0.1 ± 1.9 and 0.1 ± 1.3 mm, respectively, for thoracic tumours, −0.1 ± 1.1, 0.2 ± 1.4 and −0.1 ± 1.5 mm, respectively, for abdominal-pelvic tumours. Isotropic planning margins of 3.4, 6.1 and 5.4 mm were generated with linear addition of internal margin (IM) to CTV for the head and neck, thoracic and abdominal-pelvic tumours, respectively, while margins were only 2.4, 4.4 and 3.9 mm, respectively, if IM was added in quadrature.ConclusionsUtilizing CBCT measurements before and after treatment to detect intrafraction tumour position errors was clinically feasible. The detected intrafraction errors could be applied to improve the accuracy of radiation delivery.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Radiotherapy and Oncology - Volume 89, Issue 3, December 2008, Pages 311–319
نویسندگان
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