کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2175464 1093842 2007 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Why polyps regenerate and we don't: Towards a cellular and molecular framework for Hydra regeneration
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Why polyps regenerate and we don't: Towards a cellular and molecular framework for Hydra regeneration
چکیده انگلیسی

The basis for Hydra's enormous regeneration capacity is the “stem cellness” of its epithelium which continuously undergoes self-renewing mitotic divisions and also has the option to follow differentiation pathways. Now, emerging molecular tools have shed light on the molecular processes controlling these pathways. In this review I discuss how the modular tissue architecture may allow continuous replacement of cells in Hydra. I also describe the discovery and regulation of factors controlling the transition from self-renewing epithelial stem cells to differentiated cells.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Developmental Biology - Volume 303, Issue 2, 15 March 2007, Pages 421–433
نویسندگان
,