کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2178626 1549711 2011 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Centromere regulation: New players, new rules, new questions
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش گیاه شناسی
پیش نمایش صفحه اول مقاله
Centromere regulation: New players, new rules, new questions
چکیده انگلیسی

Centromeres support the assembly of the kinetochore on every chromosome and are therefore essential for the proper segregation of sister chromatids during cell division. Centromere identity is regulated epigenetically through the presence of the histone H3 variant CENP-A. CENP-A regulation and incorporation specifically into centromeric nucleosomes are the matter of intensive studies in many different model organisms. Here we briefly review the current knowledge in centromere biology with a focus on Drosophila melanogaster and how these insights lead to new rules and challenges.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Cell Biology - Volume 90, Issue 10, October 2011, Pages 805–810
نویسندگان
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