کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
231886 1427463 2007 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Management and control of modifier content in preparative SFC solvent cycles
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Management and control of modifier content in preparative SFC solvent cycles
چکیده انگلیسی

The objective of this work was to establish a solvent cycle with a possibility for modifier control in a preparative supercritical fluid chromatography simulated moving bed plant (SFC-SMB). Fourier transform infrared (FTIR) spectroscopy and flame ionization detection (FID) have been investigated for measuring alcohol concentrations in supercritical carbon dioxide. The integration of these in-line techniques into a modifier control schema allowed the operation of a closed loop SFC-SMB cycle. The applicability of the developed control concept for usage of 2-propanol in supercritical carbon dioxide has been verified by an experimental test series involving an eight column SFC-SMB plant. Different process variations have been compared in terms of energy and solvent consumption. Hereby, savings of almost all CO2 and 76% modifier could be achieved.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Supercritical Fluids - Volume 43, Issue 2, December 2007, Pages 204–213
نویسندگان
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