Colletotrichum truncatum species complex: Treatment considerations and review of the literature for an unusual pathogen causing fungal keratitis and endophthalmitis

• Colletotrichum species infections in humans are rare.
• We present a case of Colletotrichum truncatum species complex keratitis and endophthalmitis.
• Oral triazole was contraindicated due to concurrent tamsulosin use.
• A multidisciplinary approach is essential for timely diagnosis and tailoring of treatment.
• Further study needed to determine optimal management of Colletotrichum infections.

We present a case of Colletotrichum truncatum species complex fungal keratitis and endophthalmitis in an 87-year-old immunocompetent male in whom oral triazole antifungals were contraindicated. The patient had recently returned from 4 months in Jamaica with a one month history of progressively increasing pain and inflammation in his left eye. Corneal samples grew a filamentous fungus and internal transcribed spacer sequencing polymerase chain reaction confirmed the presence of C. truncatum species complex. Samples showed no microbial growth.