کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2428655 | 1553532 | 2006 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Characterization of monoclonal antibodies directed against the canine distemper virus nucleocapsid protein
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Characterization of monoclonal antibodies directed against the canine distemper virus nucleocapsid protein Characterization of monoclonal antibodies directed against the canine distemper virus nucleocapsid protein](/preview/png/2428655.png)
چکیده انگلیسی
We have established four monoclonal antibodies (MAbs) against the nucleocapsid protein (NP) of canine distemper virus (CDV). A competitive binding assay has revealed that the MAbs are directed against two antigenic domains. An immunofluorescence assay using a series of deletion clones of the NP and an immunoprecipitation assay using the NP have revealed that two of the MAbs recognize the C-terminal region of the NP while the other two recognize the tertiary structure of the N-terminal domain. These MAbs reacted with all eight strains of CDV used in this study, but showed different reactivities against measles virus and rinderpest virus.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Comparative Immunology, Microbiology and Infectious Diseases - Volume 29, Issues 2–3, March–May 2006, Pages 157–165
Journal: Comparative Immunology, Microbiology and Infectious Diseases - Volume 29, Issues 2–3, March–May 2006, Pages 157–165
نویسندگان
Munemitsu Masuda, Hiroki Sato, Hiroshi Kamata, Tomoe Katsuo, Akiko Takenaka, Ryuichi Miura, Misako Yoneda, Kyoko Tsukiyama-Kohara, Kiyohisa Mizumoto, Chieko Kai,