کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2429963 | 1106532 | 2007 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Distribution of the professional phagocytic granulocytes of the bony fish gilthead seabream (Sparus aurata L.) during the ontogeny of lymphomyeloid organs and pathogen entry sites
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کلمات کلیدی
DABPBSTeleostsmAbDPHPBTAGSBSA - BSAH&E - H & Ebovine serum albumin - آلبومین سرم گاوMonoclonal antibody - آنتی بادی مونوکلونالOntogeny - انتگرالInnate immunity - ایمنی ذاتیImmunohistochemistry - ایمونوهیستوشیمیIHC - ایمونوهیستوشیمیThymus - تیموسIntestine - رودهdays post-hatching - روز بعد از اخراجSpleen - طحالPhosphate-buffered saline - محلول نمک فسفات با خاصیت بافریhaematoxylin and eosin - هماتوکسیلین و ائوزینHead kidney - کلیه سرacidophilic granulocytes - گرانولوسیت اسیدوفیلیکGills - گیلز
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شناسی تکاملی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Distribution of the professional phagocytic granulocytes of the bony fish gilthead seabream (Sparus aurata L.) during the ontogeny of lymphomyeloid organs and pathogen entry sites Distribution of the professional phagocytic granulocytes of the bony fish gilthead seabream (Sparus aurata L.) during the ontogeny of lymphomyeloid organs and pathogen entry sites](/preview/png/2429963.png)
چکیده انگلیسی
Although it is believed that fish fry depend fundamentally on their innate defence mechanisms, the ontogeny of fish innate immune cells is poorly understood. In the present study, we have used a specific monoclonal antibody against acidophilic granulocytes (AGs), the main professional phagocytic cell type of the bony fish gilthead seabream, to study their localization during the development of the main lymphomyeloid organs, namely the head kidney, spleen and thymus, and of the two major portals for pathogen entry, namely the gills and intestine. AGs were observed in the posterior intestine and in the blood earlier than in the haematopoietic kidney (21 vs. 27 days post-hatching, dph). AGs were observed scattered between other cells of the haematopoietic lineage in the head kidney of larvae, but were grouped around the blood vessels of this organ in juveniles and adults, where they were also much more numerous. In the spleen and in the thymus, AGs were observed much later (62Â dph) and appeared scattered. AGs were also observed in the gill lamella and the posterior intestine near the anus throughout development.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Developmental & Comparative Immunology - Volume 31, Issue 10, 2007, Pages 1024-1033
Journal: Developmental & Comparative Immunology - Volume 31, Issue 10, 2007, Pages 1024-1033
نویسندگان
Iván Mulero, Elena Chaves-Pozo, Alicia GarcÃa-Alcázar, José Meseguer, Victoriano Mulero, Alfonsa GarcÃa Ayala,