کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2431621 1106764 2014 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Protective effect of chitin and chitosan enriched diets on immunity and disease resistance in Cirrhina mrigala against Aphanomyces invadans
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم آبزیان
پیش نمایش صفحه اول مقاله
Protective effect of chitin and chitosan enriched diets on immunity and disease resistance in Cirrhina mrigala against Aphanomyces invadans
چکیده انگلیسی


• WBC, RBC, Ht increased in 1% chitin and chitosan diets from weeks 1 to 4.
• Total protein and albumin significantly increased in all diet on weeks 2 and 4.
• Phagocytic and lysozyme activities enhanced in both diet on weeks 2 and 4.
• Complement activity was enhanced in chitosan diet from weeks 1 to 4.
• Cumulative mortality was low in fish fed with 1% of chitin and chitosan diets.

The effect of diet enriched with 1% chitin or chitosan on innate immune response and disease resistance in Cirrhina mrigala against Aphanomyces invadans was investigated at weeks 1, 2, and 4. In the un-infected and infected groups the white blood cells (WBC), red blood cells (RBC), haematocrit (Ht), lympocytes, monocytes, and neutrophils significantly increased when fed with 1% chitin (CH) or chitosan (CT) enriched diet from weeks 1 to 4 when compared to control; however, the haemoglobin (Hb) and thrombocytes significantly increased only on weeks 2 and 4. The total protein and albumin levels also significantly increased with any enriched diet on weeks 2 and 4; but the globulin and albumin:globulin ratio increased on week 4 as compared to control; similarly the phagocytic activity significantly increased on weeks 2 and 4 while the lysozyme activity increased from weeks 1 to 4. The complement activity was significantly enhanced in CT and CTI fed groups on weeks 2 and 4. In un-infected fish fed with 1% CH and CT diets, the cumulative mortality was 10% and 5% whereas the infected fish suffered 20% and 25% mortality. The present results suggest that infected fish fed with 1% chitin or chitosan enriched diet modulates the immune system conferring disease resistance in C. mrigala against A. invadans.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fish & Shellfish Immunology - Volume 39, Issue 2, August 2014, Pages 378–385
نویسندگان
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