کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2438369 | 1553771 | 2010 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Expression of Interferon-α and Mx Protein in the Livers of Pigs Experimentally Infected with Swine Hepatitis E Virus
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم دامی و جانورشناسی
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چکیده انگلیسی
SummaryExpression of interferon-α (IFN-α) and Mx protein in the livers of pigs experimentally infected with swine hepatitis E virus (HEV) was examined immunohistochemically. Five infected and five non-infected pigs were killed at 3, 7, 14, 21, 29 and 50 days post-inoculation (dpi). Tissues were collected from each pig at necropsy. Multifocal lymphoplasmacytic hepatitis (P = 0.042) and focal hepatocellular necrosis (P = 0.037) were significantly more frequent in the swine HEV-infected pigs than in the non-infected control pigs. Immunohistochemical analysis detected expression of IFN-α and Mx protein by macrophages/Kupffer cells, lymphocytes and hepatocytes in the livers of infected pigs.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Comparative Pathology - Volume 142, Issues 2–3, February–April 2010, Pages 187–192
Journal: Journal of Comparative Pathology - Volume 142, Issues 2–3, February–April 2010, Pages 187–192
نویسندگان
Y.H. Lee, Y. Ha, C. Chae,