کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2438695 | 1553777 | 2007 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Tracheobronchial Neuroendocrine Carcinoma in a Cat Tracheobronchial Neuroendocrine Carcinoma in a Cat](/preview/png/2438695.png)
SummaryA tracheobronchial neuroendocrine carcinoma in a 10-year-old cat with a history of coughing, dyspnoea and anorexia is described. Endoscopic examination revealed a yellowish mass protruding into the trachea and partly obstructing the right bronchial lumen. Histological examination of biopsy samples revealed a hypercellular tumour consisting of sheets or ribbons of small hyperchromatic cells, with oval to spindle-shaped nuclei and minimal cytoplasm; nucleoli and mitotic activity were absent. The findings were confirmed on post-mortem examination. The small neoplastic cells were immunolabelled to varying degrees by antibodies against neuron-specific enolase, S-100 protein, synaptophysin and vimentin. Ultrastructural studies revealed scattered neurosecretory granules and scanty cellular junctional complexes, including desmosomes and tonofilaments, in neoplastic cells.
Journal: Journal of Comparative Pathology - Volume 137, Issues 2–3, August–October 2007, Pages 165–168