کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2450268 1109643 2012 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Polymorphism and parent-of-origin effects on gene expression of CAST, leptin and DGAT1 in cattle
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش تغذیه
پیش نمایش صفحه اول مقاله
Polymorphism and parent-of-origin effects on gene expression of CAST, leptin and DGAT1 in cattle
چکیده انگلیسی

This study aimed to investigate differential allele expression (DAE) and polymorphism and parent-of-origin effects on expression of genes related to beef traits. CAST, related to meat tenderness, and DGAT1 and leptin, related to fat deposition, were evaluated. In bovine fetal tissues CAST was expressed twice as much (P < 0.05) in muscle of homozygous GG than in heterozygous AG. Leptin was expressed about one-tenth as much (P < 0.05) in heterozygous TpCm (allele T of paternal origin and allele C of maternal origin) than in homozygous CC. No DAE was observed. The evidence of polymorphism effect on expression of CAST and parent-of-origin effect on leptin contributes to a better understanding of events controlling the expression of genes of economic interest in cattle. Furthermore, if the parent-of-origin effects observed in fetal tissues are confirmed in adult tissues and associated to phenotypic variation, this parental origin criterion may be considered in marker-assisted selection of beef traits.


► Gene expression of CAST was affected by polymorphism in cattle.
► Gene expression of leptin was affected by parental origin in cattle.
► Absence of differential allelic expression of CAST and DGAT1 in bovine fetal tissues.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Meat Science - Volume 90, Issue 2, February 2012, Pages 507–510
نویسندگان
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