کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2454736 1554313 2015 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effects of dietary selenium on host response to necrotic enteritis in young broilers
ترجمه فارسی عنوان
اثرات سلنیوم بر روی پاسخ میزبان به آنترویکتروئید در جوجههای گوشتی
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
چکیده انگلیسی


• Optimum organic selenium dose for enhancing gut health was determined in poultry.
• Selenium-fed broiler chickens showed reduced serum Clostridium toxins after NE infection.
• Dietary selenium enhanced serum antibody levels to Clostridium toxins.
• Dose-dependent effect of selenium on intestinal cytokine response was shown.
• Feeding organic selenium enhanced intestinal beta-defensins expression.

The effects of dietary supplementation of young broiler chickens with an organic selenium (Se) formulation, B-Traxim Se, on experimental necrotic enteritis (NE) were studied. Chickens treated with three Se doses (0.25, 0.50, 1.00 mg/kg) from hatch were orally challenged with Eimeria maxima at 14 days of age followed by Clostridium perfringens to induce NE. Chickens fed with 0.50 mg/kg Se showed significantly increased body weights and antibody levels against NetB, and significantly reduced gut lesions compared with non-supplemented chickens. However, there were no significant differences in Eimeria oocyst shedding between the Se-treated and non-supplemented groups. Levels of IL-1β, IL-6, IL-8, iNOS, LITAF, TNFSF15, AvBD6, AvBD8, and AvBD13 transcripts were increased in the gut and spleen of at least one of the three Se-treated groups compared with the non-treated group. These results suggest that dietary supplementation of young broilers with Se might be beneficial to reduce the negative consequence of NE.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Research in Veterinary Science - Volume 98, February 2015, Pages 66–73
نویسندگان
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