کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2456540 | 1110545 | 2007 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Cardiopulmonary bypass influences the plasma levels of calcitonin gene-related peptides in dogs: Effects of hemofiltration and hemodilution
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم دامی و جانورشناسی
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![عکس صفحه اول مقاله: Cardiopulmonary bypass influences the plasma levels of calcitonin gene-related peptides in dogs: Effects of hemofiltration and hemodilution Cardiopulmonary bypass influences the plasma levels of calcitonin gene-related peptides in dogs: Effects of hemofiltration and hemodilution](/preview/png/2456540.png)
چکیده انگلیسی
Calcitonin gene-related peptides (CGRP), which are potent vasodilators, are elevated during cardiopulmonary bypass (CPB) in humans. We evaluated the plasma levels of CGRP in dogs during CPB with hemofiltration with and without hemodilution. Female beagles were divided into control (n = 5) and hemodilution (n = 5) groups. The CPB with hemofiltration was performed with or without hemodilution. For the measurement of CGRP, blood samples were collected pre-CPB, during CPB, and post-CPB. The concentrations of CGRP in the hemofiltration solution were measured. Although the CPB elevated the plasma CGRP levels in both groups, its elevation was significant in the hemodilution group when compared to the pre-CPB levels. CGRP levels returned to normal post-CPB. Significant differences were found between the two groups in the CGRP amount in hemofiltration. The results show that hemofiltration should be used during CPB to decrease the plasma levels of CGRP.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Research in Veterinary Science - Volume 82, Issue 1, February 2007, Pages 110-114
Journal: Research in Veterinary Science - Volume 82, Issue 1, February 2007, Pages 110-114
نویسندگان
Mitsuhiro Isaka, Michiaki Imamura, Ichiro Sakuma, Yutaka Makino, Norihiko Shiiya, Keishu Yasuda,