کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2456573 1110547 2006 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Abomasal contents of parasitised sheep contain an inhibitor of gastrin secretion in vitro
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
Abomasal contents of parasitised sheep contain an inhibitor of gastrin secretion in vitro
چکیده انگلیسی

Serum gastrin concentrations are typically elevated in parasitised sheep; however, in some animals serum gastrin concentrations may fall abruptly despite a very high abomasal pH. Although proliferating abomasal bacteria in culture generate a potent inhibitor of in vitro gastrin secretion, this inhibitor has not been detected in abomasal contents of unparasitised sheep. In sheep parasitised by O. circumcincta, all abomasal fluid samples of pH 5 and above were inhibitory to gastrin release in vitro. Inhibitory activity and abomasal pH were correlated in two separate experiments; the model best fitting the data being sigmoidal in each case, with zero activity at pH 3.6 and 4.6, respectively. There was no clear evidence that the presence of a gastrin inhibitor in the abomasal contents reduced the serum gastrin concentration in parasitised sheep. Serum gastrin was correlated with abomasal pH (log10 serum gastrin concentrations conformed to log-linear sigmoidal models).

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Research in Veterinary Science - Volume 81, Issue 2, October 2006, Pages 225–230
نویسندگان
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