کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2473226 1555916 2015 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The ‘emergence’ of turnip mosaic virus was probably a ‘gene-for-quasi-gene’ event
ترجمه فارسی عنوان
ظهور احتمالا یک ویروس موزائیک روپوش یک ژن برای ژن شبه؟ رویداد
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ویروس شناسی
چکیده انگلیسی


• Taxonomies of plant viruses and their hosts are rarely congruent.
• Rates of host switching by plant viruses in nature are unknown.
• Genome-wide SNPs appeared when TuMV infected a novel host.
• Host specificity probably determined by ephemeral SNP combinations.

Turnip mosaic potyvirus is a virus of brassicas that emerged from a lineage of monocotyledon-infecting potyviruses about 1000 years ago. In vivo and in silico studies all indicate that sites, primarily in its protein 3 (P3) and cylindrical inclusion protein (CI) genes, but also its small 6 kDa 2 protein (6K2) and genome-linked viral protein (VPg) genes, control host specificity in a dynamic way. It is most likely that non-unique combinations of transient viral genomic single nucleotide polymorphisms (SNPs), not all of them non-synonymous, allowed the host switch to occur. These SNPs were probably ephemeral and replaced over time by other combinations as the population subsequently diverged within, and adapted to, the brassica host population.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Virology - Volume 10, February 2015, Pages 20–26
نویسندگان
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