Étude des interactions entre oligosaccharides impliqués dans l'adhésion cellulaire. Exemple du trisaccharide Lewisx

Nature often chooses weak molecular interactions for playing important role in cellular recognition and adhesion. These interactions involve particularly oligosaccharides, which are the structural elements present at the most exterior surface of the cell. Three oligosaccharides were prepared for study of the interaction by vesicle micromanipulation technique. This study allowed us to measure directly, for the first time, a carbohydrate-carbohydrate interaction.