کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2482818 1556298 2006 17 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The role of transporters in drug interactions
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی اکتشاف دارویی
پیش نمایش صفحه اول مقاله
The role of transporters in drug interactions
چکیده انگلیسی

Transport proteins play an important role in the adsorption, distribution and elimination of a wide variety of drugs. Therefore, it is not surprising that transporter-based drug interactions can occur in the clinic. These interactions can lead to changes in toxicity and/or efficacy of the affected drug. Here, we review such interactions and ask if these interactions could have been predicted from in vitro data. Conducting such in vitro–in vivo correlation is important for predicting future transporter-based drug interactions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Pharmaceutical Sciences - Volume 27, Issue 5, April 2006, Pages 501–517
نویسندگان
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