کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2507351 | 1117485 | 2014 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Linearity study on detection and quantification limits for the determination of avermectins using linear regression Linearity study on detection and quantification limits for the determination of avermectins using linear regression](/preview/png/2507351.png)
In this study, linear relationships between response and concentration were used to estimate the detection limit (DL) and quantification limit (QL) for five avermectins: emamectin, abamectin, doramectin, moxidectin, and ivermectin. Estimation of DL and QL was based on the standard deviation of residual and y-intercept of the regression line at low concentrations of avermectins, using the dispersive solid-phase extraction procedure. Avermectin extracts were analyzed using liquid chromatography tandem mass spectrometry. Based on the regression slope, DL and QL were higher at concentrations of 0.3–0.4 μg/kg and 1 μg/kg, respectively, for all avermectin compounds. Linearity assessment was performed by linear regression, which incorporated a regression model, outlier rejection, and evaluation of the assumption with a significant test. For all avermectins, there is a significant correlation between response and concentration in the range 1–15 μg/kg, and the y-intercept passes through origin (zero).
Journal: Journal of Food and Drug Analysis - Volume 22, Issue 4, December 2014, Pages 407–412