کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2526170 1558010 2016 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Leojaponic acids A and B, two new homologous terpenoids, isolated from Leonurus japonicus
ترجمه فارسی عنوان
اسیدهای A و B Leojaponic، دو terpenoids جدید همولوگ، جدا شده از Leonurus japonicus
کلمات کلیدی
Leonurus japonicus؛ اسید japonicus ؛ padeafoot
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی طب مکمل و جایگزین
چکیده انگلیسی

The present study aimed at isolation and purification of the bioactive terpenoids from the herb of Leonurus japonicus by chromatographic separations such as silica gel, sephadex LH-20 and C18 reversed phase silica gel, as well as preparative HPLC. As a result, leojaponic acids A (1, C17H24O4) and B (2, C18H26O4), two homologous terpenoids, together with (−)-loliolide (3), 1-(3-ethylphenyl) ethane-1, 2-diol (4) and dibutyl phthalate (5), were isolated from the EtOH extract of L. japonicus. All the chemical structures of the isolates were elucidated on the basis of 1D and 2D NMR analyses. Compounds 1 and 2 were new terpenoids, and Compounds 3 and 4 were isolated and identified for the first time from this plant. In addition, the α-glucosidase and tyrosinase inhibitory activity of the new compounds were evaluated.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chinese Journal of Natural Medicines - Volume 14, Issue 4, April 2016, Pages 303–307
نویسندگان
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