کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2538246 | 1559637 | 2016 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
6(17)-Epoxylathyrane diterpenes from Euphorbia sogdiana Popov with cytotoxic activity
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موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
داروشناسی
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چکیده انگلیسی
Phytochemical analysis of Euphorbia sogdiana Popov, Euphorbiaceae, afforded the isolation of three new diterpenes based on the rare 6(17)-epoxylathyrane skeleton (1–3), along with a lathyrane (4), a myrsinane (5) and a tigliane (6) diterpenoids, previously isolated from Euphorbia aellenii. Their chemical structures were established through a combination of nuclear magnetic resonance spectroscopy and mass spectrometric methods. The epoxylathyranes 1–4 were tested to evaluate their cytotoxic activity against Jurkat T-leukemia and EJ-138 bladder cancer cells and their chemical analogy allowed to propose some structure activity relationships.
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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fitoterapia - Volume 108, January 2016, Pages 87–92
Journal: Fitoterapia - Volume 108, January 2016, Pages 87–92
نویسندگان
Zeinab Yazdiniapour, Mustafa Ghanadian, Behzad Zolfaghari, Virginia Lanzotti,