کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2538277 | 1559643 | 2015 | 4 صفحه PDF | دانلود رایگان |
Three new labdane-type diterpene glycosides, 15,18-di-O-β-d-glucopyranosyl-13(E)-ent-labda-7(8),13(14)-diene-3β,15,18-triol (1), 15,18-di-O-β-d-glucopyranosyl-13(E)-ent-labda-8(9),13(14)-diene-3β,15,18-triol (2), and 15-O-β-d-apiofuranosyl-(1 → 2)-β-d-glucopyranosyl-18-O-β-d-glucopyranosyl-13(E)-ent-labda-8(9),13(14)-diene-3β,15,18-triol (3), were isolated from the fruits of Rubus chingii. Their structures were elucidated on the basis of spectroscopic data and chemical methods. The cytotoxic activities of compounds 1–3 were evaluated against five human tumor cell lines (HCT-8, BGC-823, A549, and A2780). Compounds 3 showed cytotoxic activity against A549 with an IC50 value of 2.32 μM.
Three new labdane-type diterpene glycosides (1–3) were isolated from the fruits of Rubus chingii. Compound 3 showed cytotoxic activity against A549 with an IC50 value of 2.32 μM.Figure optionsDownload high-quality image (278 K)Download as PowerPoint slide
Journal: Fitoterapia - Volume 102, April 2015, Pages 23–26