کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2538294 1559643 2015 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Antimicrobial and cytotoxic constituents from native Cameroonian medicinal plant Hypericum riparium
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی داروشناسی
پیش نمایش صفحه اول مقاله
Antimicrobial and cytotoxic constituents from native Cameroonian medicinal plant Hypericum riparium
چکیده انگلیسی

Bioassay guided fractionation of Hypericum riparium leaves extract has resulted in the isolation and characterization of three new compounds namely chipericumin E (1), hyperenone C (3), and hyperixanthone (5), together with twenty known compounds. Their structures were elucidated based on comprehensive interpretation of spectroscopic and spectrometric data. Compounds 1–4, and 6–8 displayed moderate antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) and cytotoxic effects on the human gastric cell line BGC-823 with IC50 values ranging from 6.54 to 18.50 μM.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fitoterapia - Volume 102, April 2015, Pages 149–155
نویسندگان
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