کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2538385 | 1559640 | 2015 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Four new phenanthrenoid dimers from Juncus effusus L. with cytotoxic and anti-inflammatory activities
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
داروشناسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Four new phenanthrenoid dimers from Juncus effusus L. with cytotoxic and anti-inflammatory activities Four new phenanthrenoid dimers from Juncus effusus L. with cytotoxic and anti-inflammatory activities](/preview/png/2538385.png)
چکیده انگلیسی
Four new phenanthrenoid dimers, effususins A–D (1–4), were isolated from an ethanolic extract of the medullae of Juncus effuses (Juncaceae). Their structures were elucidated by 1D and 2D NMR spectroscopic analysis and mass spectrometry. Compounds 1–4 was in vitro evaluated for their cytotoxic activities by CCK-8 assay against five human cancer cell lines (SHSY-5Y, SMMC-7721, HepG2, Hela, and MCF-7) and their inhibitory effects on NO production in lipopolysaccharide-activated murine macrophage RAW264.7 cells. Effususin B exhibited moderate to strong cytotoxic activities against the tested cancer cell lines and moderate anti-inflammatory activity.
Figure optionsDownload high-quality image (230 K)Download as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fitoterapia - Volume 105, September 2015, Pages 83–88
Journal: Fitoterapia - Volume 105, September 2015, Pages 83–88
نویسندگان
Wei Ma, Feng Liu, Yun-Yun Ding, Yue Zhang, Ning Li,