کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2538950 1122160 2012 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cytotoxic nor-dammarane triterpenoids from Dysoxylum hainanense
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی داروشناسی
پیش نمایش صفحه اول مقاله
Cytotoxic nor-dammarane triterpenoids from Dysoxylum hainanense
چکیده انگلیسی

Four new nor-dammarane triterpenoids, 12β-O-acetyl-15α,28-dihydoxy-17β-methoxy-3-oxo-20,21,22–23,24,25,26,27-octanordammanran (1), 12β-O-acetyl-15α,17β,28-trihydoxy-3-oxo-20,21,22–23,24,25,26,27-octanordammanran (2), 12β-O-acetyl-15α,28-dihydoxy-3-oxo-17-en-20,21,22–23,24,25,26,27-octanordammanran (3), and 12β,15α,17β,28-tetrahydoxy-3-oxo-20,21,22–23,24,25,26,27-octanordammanran (4), were isolated from the 70% EtOH extract of Dysoxylum hainanense. The structures of the new compounds were elucidated by spectral methods. All the triterpenoids were in vitro evaluated for their cytotoxic activities against four tumor cell lines (A549, SK-OV-3, SKMEL-2 and HCT15).

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fitoterapia - Volume 83, Issue 1, January 2012, Pages 13–17
نویسندگان
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