کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2538995 1122161 2011 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Chromones and coumarins from the dried fructus of Cnidium monnieri
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی داروشناسی
پیش نمایش صفحه اول مقاله
Chromones and coumarins from the dried fructus of Cnidium monnieri
چکیده انگلیسی

Chemical investigations on the ethanolic extract of the dried fructus of Cnidium monnieri offered three chromones and eight coumarins. Among them, a new chromone and a new coumarin were identified and elucidated as 5,7-dihydroxy-6-[(2Z)-4-(β-d-glucopyranosyl)oxy-3- methylbut-2-enyl]-2-hydroxymethyl-4H-1-benzopyran-4-one (1, hydroxycnidimoside A) and (rel 1′S,2′R)-8-(2,3-epoxy-1-hydroxy-3-methylbutyl)-7-methoxycoumarin (8, hydroxyosthole epoxide), respectively, by extensive analyses of spectroscopic data including 1- and 2-D NMR, MS, UV, OR, IR, and HRMS data. The other known compounds were identified by analyses of spectroscopic data and by comparison with literature reported.

A new chromone and a new coumarin were isolated from the ethanolic extract of the dried fructus of Cnidium monnieri. Their structures were identified and elucidated as 5,7-dihydroxy-6-[(2Z)-4-(β-d-glucopyranosyl)oxy-3-methylbut-2-enyl]-2-hydroxymethyl-4H-1-benzopyran-4-one and (rel 1′S,2′R)-8-(2,3- epoxy-1-hydroxy-3-methylbutyl)-7- methoxycoumarin, respectively, by extensive analyses of spectroscopic data.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fitoterapia - Volume 82, Issue 5, July 2011, Pages 767–771
نویسندگان
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