کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2539060 | 1122163 | 2010 | 6 صفحه PDF | دانلود رایگان |
The antipruritic effects of the ethanol fractions of Humulus scandens on the 4-AP (4-aminopyridine)-induced and chloroquine-induced scratching in ICR mice were examined. The 40% ethanol fractions of H. scandens suppressed both the 4-AP- and chloroquine-induced scratching behavior, which significantly inhibited degranulation of rat peritoneal mast cell and antigen-stimulated histamine release. Further studies proved that the 40% ethanol fractions of H. scandens decreased the content of IL4 in serum of chloroquine-induced scratching ICR mice. The results suggest that the 40% ethanol fractions of H. scandens has antipruritic effects on both antihistamine-resistant and -sensitive pruritus.
The antipruritic effects of the ethanol elutions of H. scandens on the 4-AP-induced and chloroquine-induced scratching in ICR mice were examined. The 40% ethanol elution suppressed both scratching behavior.Figure optionsDownload as PowerPoint slide
Journal: Fitoterapia - Volume 81, Issue 8, December 2010, Pages 1073–1078