کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2539110 | 1122165 | 2011 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: The potent anti-inflammatory agent escin does not increase corticosterone secretion and immune cell apoptosis in mice The potent anti-inflammatory agent escin does not increase corticosterone secretion and immune cell apoptosis in mice](/preview/png/2539110.png)
Escin exerts potent glucocorticoid-like anti-inflammatory effects. The aim of this study was to investigate whether the anti-inflammatory effect of escin is through the up-regulation of glucocorticoids and if escin induces pathological changes in immune organs. Mice were administrated with escin intravenously for 7 days before observing the relevant parameters. The results showed that escin exhibits a potent anti-inflammatory effect, but does not increase corticosterone secretion in mice, and does not increase immune cell apoptosis in the spleen and thymus of mice. These findings suggest that the anti-inflammatory effect of escin is not dependent on the release of corticosterone.
Chemical structure of escin.Figure optionsDownload as PowerPoint slide
Journal: Fitoterapia - Volume 82, Issue 6, September 2011, Pages 861–867