Interferencia en electroforesis capilar debida a contraste yodado

Blood samples for laboratory analysis, including protein electrophoresis, were taken from two patients just after they had been subjected to a computed tomography (CT) scan with iodinated contrast. A monoclonal peak was observed in the beta fraction of the electrophoresis pattern, which was unable to be confirmed by immunofixation or immunosubtraction, leading to the suspicion of interference by iodinated contrast. A second sample was requested in both cases to repeat the analysis, which showed the disappearance of the peak, with a totally normal electrophoretic profile being obtained.