کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2582811 1561698 2016 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Alteration in bone geometric and mechanical properties, histomorphometrical parameters of trabecular bone, articular cartilage, and growth plate in adolescent rats after chronic co-exposure to cadmium and lead in the case of supplementation with green, bl
ترجمه فارسی عنوان
تغییرات در خواص هندسی و مکانیکی استخوان، پارامترهای هیستومورفومتریک استخوان ترابکولر، غضروف مفصلی و صفحه رشد در موش های صحرایی پس از مواجهه با کادمیوم و سرب در مواجهه با مکمل سبز،
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست بهداشت، سم شناسی و جهش زایی
چکیده انگلیسی


• The exposure to Cd and Pb in adolescent rats was studied.
• Cd and Pb was given within the limits of human environmental exposure.
• All the rats were administered with different type of teas.
• It is difficult to indicate which tea has the best protective effects on bone and hyaline cartilage against heavy metal action.

Adolescent male Wistar rats were used to check whether regular consumption of black, red, white, or green tea would have a protective effect on femur development during 12-week exposure to Cd and Pb (7 mg Cd and 50 mg Pb in 1 kg of the diet). The animals were randomly divided (n = 12) into a positive control (without Cd, Pb and teas), a negative control group (Cd and Pb), and groups supplemented additionally with green (GT), black (BT), red (RT), and white tea (WT). Heavy metals reduced the geometric and densitometric parameters and the total thickness of articular cartilage irrespective of tea administration and influenced mechanical endurance, growth plate thickness, and trabecular histomorphometry depending on the tea type. It is difficult to indicate which tea has the best protective effects on bone and hyaline cartilage against heavy metal action.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Environmental Toxicology and Pharmacology - Volume 46, September 2016, Pages 36–44
نویسندگان
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