کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2583622 | 1130696 | 2014 | 9 صفحه PDF | دانلود رایگان |
• Significant lethal and sublethal effects of Nonylphenol on Rhinella arenarum embryos and larvae were reported.
• Stage-dependent susceptibility to Nonylphenol was informed.
• A high teratogenic potential of Nonylphenol was reported.
• The study showed the high risk that Nonylphenol might represent to amphibian's populations.
The toxicity of Nonylphenol, an emerging pollutant, on the common South American toad Rhinella arenarum was stage and time dependent, thus Median Lethal Concentrations (LC50) for acute (96 h), short-term chronic (168 h) and chronic exposure (336 h) were 1.06; 0.96 and 0.17 mgNP/L from embryonic period (S.4), whereas for exposure from larvae (S.25), LC50 remained constant at 0.37 mgNP/L from 96 h to 168 h, decreasing to 0.11 mgNP/L at 336 h. NOEC-168 h for exposure from embryos was 0.025 mgNP/L. The Teratogenic Potential (NOEC-lethality/NOEC-sublethal effects) was 23 times higher than the threshold value, indicating a high risk for embryos to be malformed in absence of significant lethality and representing a threat for the species conservation. By comparing with other amphibians, the early development of R. arenarum was very sensitive to NP. The results highlight the relevance of extending the exposure time and look for the most sensitive stage in order to perform the bioassays for conservation purposes.
Journal: Environmental Toxicology and Pharmacology - Volume 38, Issue 2, September 2014, Pages 634–642