کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2629594 | 1136589 | 2007 | 11 صفحه PDF | دانلود رایگان |
SummaryObjectiveSystematic assessment of the in vitro research on high potency effects.MethodPublications of experiments were collected through databases, experts, previous reviews, citation tracking. Inclusion criteria: stepwise agitated dilutions <10−23; cells or molecules from human or animal. Experiments were assessed with the modified SAPEH score.ResultsFrom 75 publications, 67 experiments (1/3 of them replications) were evaluated. Nearly 3/4 of them found a high potency effect, and 2/3 of those 18 that scored 6 points or more and controlled contamination. Nearly 3/4 of all replications were positive. Design and experimental models of the reviewed experiments were inhomogenous, most were performed on basophiles.ConclusionsEven experiments with a high methodological standard could demonstrate an effect of high potencies. No positive result was stable enough to be reproduced by all investigators. A general adoption of succussed controls, randomization and blinding would strengthen the evidence of future experiments.
Journal: Complementary Therapies in Medicine - Volume 15, Issue 2, June 2007, Pages 128–138