کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2663126 | 1140545 | 2006 | 8 صفحه PDF | دانلود رایگان |
Multiple myeloma is a progressive hematologic disease characterized by an excessive number of abnormal plasma cells that infiltrate the bone marrow by the overproduction of monoclonal immunoglobulin (IgG, IgA, IgD, or IgE) or Bence-Jones protein that is secreted into the blood and urine. It is the second-most prevalent hematologic disease and makes up 10%-15% of all hematological malignancies (leukemia and lymphoma). Multiple myeloma accounts for 1% of all cancers and causes 2% of all cancer deaths. Patients often present to their primary care nurse practitioner with one or more nonspecific symptoms such as new-onset bone pain, fatigue, recurrent infections, anemia, hypercalcemia, or renal insufficiency. Early recognition and referral by primary care nurse practitioners may extend the survival of patients from months to years.
Journal: The Journal for Nurse Practitioners - Volume 2, Issue 10, November–December 2006, Pages 665–672