Advances in Hormonal Therapy for Breast Cancer

ObjectivesTo describe recent developments in hormonal therapy for breast cancer, focusing on SERMs and AIs.Data SourcesPublished journal articles and texts, research reports and monographs, government publications, and professional organization guidelines.ConclusionResearch continues to identify the effectiveness of hormonal therapy in breast cancer, including adjuvant treatment in early and advanced stages as well as a chemopreventive measure. The individual drug profile must be evaluated for safety and efficacy, and the impact on QOL must be considered.Implications for Nursing PracticeIt is imperative that oncology nurses understand the physiology, application, risks, and benefits of hormonal therapies.